UNIVERSITY OF FLORIDA

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Computational Neuromechanics Lab

B.J. FREGLY, PH.D.
KNOX T. MILLSAPS
PROFESSOR, AND
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION PROFESSOR

Seeking to make "computational neurorehabilitation"
a clinical reality for the design of personalized treatments for movement impairments.

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Walking motion predicted for a hemiparetic subject using a subject-specitic computational model controlled by five muscle synergies per leg (Meyer et al., Frontiers in Bioengineering and Biotechnology, 2016)

Funded Projects

Over $6.6 million in funded research, primarily as PI and primarily from the National Science Foundation and the National Institutes of Health.

Computational Design of FastFES Rehabilitation to Improve Post-Stroke Gait
National Institutes of Health National Center for Simulation in Rehabilitation Research
1/1/17-12/31/17, $30,000, PI
(Download project summary)

Development of a Muscle Adaptation in Spaceflight Simulator
National Aeronautics and Space Administration Grant
1/1/17-12/31/19, $750,000, Co-PI
(Download project summary)

CDS&E: A Next-Generation Computation Framework for Predicting Optimal Walking Motion
National Science Foundation CBET Division Grant
8/15/14-8/14/17, $499,994, PI
(Download project summary)

REU: Computational Neuromechanics for Stroke Rehabilitation
National Science Foundation CBET Division BME Grant
1/1/14-8/15/14, $7,000, PI

Driving Biological Problem: Predictive Simulations to Improve Walking in Patients Post Stroke
Stanford University (National Institutes of Health subcontract)
1/1/14-8/15/14, $34,885, PI

Computational Neuromechanics for Stroke Rehabilitation
National Science Foundation CBET Division BME Grant
8/15/12-8/14/15, $330,000, PI
(Download project summary)

Computational Wear Assessment for BiCR Knee Designs
Biomet Corporation
10/1/10-4/1/11, $27,132, PI

EAGER: Treatment Planning for Gait Pathologies Based on Whole-Body Angular and Linear Momentum
National Science Foundation CBET Division RAPD Grant
8/15/10-8/14/13, $116,841, PI
(Download project summary)

Evaluation of In Vivo Knee Load Predictions using Instrumented Implants
National Institutes of Health NIBIB R01 Grant
8/1/10-4/30/15, $2,265,174, PI
(Download project summary)
Click here to access the Knee Grand Challenge website
Click here to see geography of use of Knee Grand Challenge data sets and models

Estimating Probability of Gain in Next Cycle of Surrogate Based Design Optimization
National Science Foundation CMMI Division Grant
9/1/09-8/31/12, $250,000, Co-PI

Computational Simulation of Knee Osteoarthritis Development
National Science Foundation CBET Division BME Grant
1/1/09-12/31/11, $239,989, PI
(Download project summary)

Real-Time Model-Based Gait Retraining for Knee Osteoarthritis Rehabilitation
National Institutes of Health NCMRR R21 Grant
9/12/07-8/31/10, $384,368, PI
(Download project summary)

IREE: Surrogate-Based Modeling of Joint Contact Mechanics
National Science Foundation CBET Division BME Grant
8/16/07-4/30/09,
$15,318, PI

Computational Contact Pressure Testing of Knee Replacement Design Concepts
Encore Medical Corporation
1/1/07-6/1/07, $24,000, PI

Surrogate-Based Modeling of Joint Contact Mechanics
National Science Foundation CBET Division BME/RAPD Grant
5/1/06-4/30/09, $270,000, PI
(Download project summary)

Design and Computational Analysis of Novel Knee Replacement Concept
MAKO Surgical Corporation
7/1/05-8/15/08, $223,488, Co-PI

Surgery Simulation of High Tibial Osteotomy - Transitional
Whitaker Foundation Biomedical Engineering Supplemental Research Grant
5/1/05-4/30/06, $80,000, PI

Virtual Testing of a Unicondylar Knee Replacement Design
Exactech Corporation
10/8/04-1/1/05, $29,000, PI

CAREER: Virtual Prototyping of Artificial Knees
National Science Foundation CBET Division RAPD CAREER Grant
5/1/03-4/30/08, $400,000, PI
(Download project summary)

Virtual Testing of a Total Knee Replacement Design
Stryker-Howmedica Osteonics Corporation
4/1/03-12/1/03, $12,500, PI

A Computational Framework for Simulating Joint Mechanics
National Institutes of Health NLM R03 Grant
5/1/02-4/30/05, $206,874, PI
(Download project summary)

Contact Stress Testing of Artificial Knees
Exactech Corporation
9/18/01-12/15/02, $22,500, PI

Surgery Simulation of High Tibial Osteotomy
Whitaker Foundation Biomedical Engineering Research Grant
9/1/01-8/31/04, $239,979, PI
(Download project summary)

Lab Handbook

Click here to download the laboratory handbook.

Presentation Suggestions

Click here to download suggestions for developing and giving effective presentations.

Writing Tips

Below are suggestions provided by three different journals for how to write a journal manuscript:
Journal of Biomechanical Engineering writing tips
Journal of Biomechanics writing tips
Journal of Orthopaedic Research writing tips