Microfluidics and BioMEMS Laboratory
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Patents
Book
Z. Hugh Fan (Ed.), "Circulating Tumor Cells: Isolaion and Analysis", John Wiley & Sons, Inc.: Hoboken, NJ, ISBN: 978-1-118-91553-0, 2016, 464 pages.
Selected publications
M. Alipanah, C. Manzanas, X. Hai, J. A. Lednicky, A. Paniz-Mondolfi, J. G. Morris, Z. H. Fan, “Mayaro virus detection by integrating sample preparation with isothermal amplification in portable devices”, Analytical and Bioanalytical Chemistry, 415, 2023, 5605–5617.
P. Dopico, M. N. Le, B. Burgess, Z. Yang, Y. Zhao, Y. Wang, T. J. George, Z. H. Fan, “Longitudinal Study of Circulating Biomarkers in Patients with Resectable Pancreatic Ductal Adenocarcinoma”, Biosensors, 12, 2022, 206.
C. Manzanas, M. M. Alam, J. C. Loeb, J. A. Lednicky, C. Y. Wu, Z. H. Fan, “A Valve-Enabled Sample Preparation Device with Isothermal Amplification for Multiplexed Virus Detection at the Point-of-Care”, ACS Sensor, 2021, 6, 4176–4184.
K. Chen, P. Dopico, J. Varillas, J. Zhang, T. J. George, Z. H. Fan, “Integration of Lateral Filter Arrays with Immunoaffinity for Circulating-Tumor-Cell Isolation”, Angewandte Chemie International Edition, 58, 2019, 7606–7610 (cover page).
X. Jiang, J. C. Loeb, C. Manzanas, J. A. Lednicky, Z. H. Fan, “Valve-enabled Sample Preparation and RNA Amplification in a Coffee Mug for Zika Virus Detection”, Angewandte Chemie International Edition, 57, 2018, 17211–17214.
W. Sheng, O. O. Ogunwobi, T. Chen, J. Zhang, T. J. George, C. Liu, and Z. H. Fan, "Capture, release and culture of circulating tumor cells from pancreatic cancer patients using an enhanced mixing chip," Lab on a Chip, 2014, 14, 89-98.
W. Sheng, T. Chen, W. Tan, and Z. H. Fan, "Multivalent DNA nanospheres for enhanced capture of cancer cells in microfluidic devices," ACS Nano, 2013, 7, 7067-7076.
C. K. Fredrickson, Z. H. Fan, “Macro-to-Micro Interface for Microfluidic Devices”, Lab on a chip, 4, 2004, 526-533.
Z. H. Fan; S. Mangru; R. Granzow; P. Heaney; W. Ho, Q. Dong; R. Kumar; “Dynamic DNA hybridization on a chip using paramagnetic beads ”, Analytical Chemistry, 71, 1999, 4851-4859.
D. J. Harrison; K. Fluri; K. Seiler; Z. Fan; C. S. Effenhauser; A. Manz, "Micromachining a miniaturized capillary electrophoresis-based chemical analysis system on a chip", Science, 261, 1993, 895-897.
A list of all journal publications
Publication listed in PubMed
Publication listed in Google Scholar
Patents
C. Y. Wu, X. Jiang, M. Pan, J. Lednicky, A. D. Theodore, Z. H. Fan, N. Afshar-Mohajer, “Bioaerosol detection systems and methods of use”, U.S. Patent 11,845,997, 2023
Z. H. Fan, C. Manzanas, M. Alipanahrostami, J. Lednicky, C-Y. Wu, “Multiplex Devices and Methods for Pathogen Detection”, PCT/US2022/76456, 2022
Z. H. Fan, K. Chen, “Lateral Filter Array Microfluidic Device”, U.S. Patent Application, 2021/0236992 A1, 2021
Z. H. Fan, X. Jiang., T. B. Tilly, J. Lednicky, C-Y. Wu, “Apparatus and Method for Performing Microorganism Detection”, U.S. Patent Application, 2021/0230533 A1, 2021
H.O. Fasanya, P. Dopico, Z. H. Fan, D.W. Siemann, “Use of Ganglioside 2 and 3 for Circulating Sarcoma Cell Detection”, PCT/US2020/053479, 2020
C. Y. Wu, X. Jiang, M. Pan, J. Lednicky, A. D. Theodore, Z. H. Fan, N. Afshar-Mohajer, “Bioaerosol detection systems and methods of use”, US Patent 10,859,473, 2020
Z. H. Fan, J. Zhang, “Antibody and aptamer ensemble for cell isolation and enrichment”,U.S. Patent 10,466,243, 2019
Z. H. Fan, K. Jackson, "Apparatuses and methods for high-throughput protein synthesis", U.S. Patent 10,214,713, 2019
Z. H. Fan, W. Sheng, T. Chen, W. Tan, “Devices and Methods for Isolating Cells”, U.S. Patent 2016/0091489 A1, 2016
Z. H. Fan, T. Nishida, “Microfluidic array device and system for simultaneous detection of multiple analytes”, PCT/US2008/058392, 2008
Z. H. Fan, S. Jin, Q. Mei, "Miniaturized in vitro protein expression array", PCT/US2006/026752, 2006
Z. H. Fan, B. J. Lutz, B. Friedrich, T. Burgdorf, “Hydrogen sensor using enzyme-catalyzed reaction”, PCT/US2006/009495, 2006
S. E. McBride; S. C. Cherukuri; R. Kumar; J. A. Ladd; Z. H. Fan; B. L. Bentz; P. J. Zanzucchi; "Apparatus for separating molecules", US Patent 6,296,752, 2001
T. L. Fare; Z. H. Fan; P. J. Heaney, “Flow control in microfluidics devices by controlled bubble formation”, US Patent 5,992,820, 1999
S. C. Cherukuri; R. R. Demers; Z. H. Fan; A. W. Levine; S. E. McBride; P. J. Zanzucchi, "Method and system for inhibiting cross-contamination in fluids of combinatorial chemistry device", US Patent 5,980,704, 1999
P. J. Zanzucchi; S. C. Cherukuri; S. E. McBride; R. R. Demers; A. W. Levine; B. J. Thaler; R. L. Quinn; P. L. Braun; W. Chiang; Z. H. Fan; S. A. Lipp; J. R. Matey, “Liquid distribution system”, US Patent 5,846,396, 1998
Z. H. Fan; A. W. Levine; S. C. Cherukuri; S. A. Lipp, “Field-assisted sealing”, US Patent 5,747,169, 1998
S. C. Cherukuri; R. R. Demers; Z. H. Fan; A. W. Levine; S. E. McBride; P. J. Zanzucchi, “Method and system for inhibiting cross-contamination in fluids of combinatorial chemistry device”, US Patent 5,603,351, 1997