Dr. Xin Tang
Associate Professor
Biography
Professor Xin Tang received his Post-doctoral training from Harvard University and Ph.D. from University of Illinois at Urbana-Champaign. His research centers at the interface of engineering, physics, chemistry, and biology. His lab studies cell and molecular mechanics in cancer, cardiovascular system, and neurons; unconventional mechano-electrophysiology; quantitative in vivo/vitro functional bio-imaging; AI/ML-powered bio-nanotechnology; and development of new biophysical tools to probe biological function/structure. His research is supported by NIH, NSF, AFOSR/DoD, UF Health Cancer Center, UF Opportunity Funds, and etc. He was awarded the NIH Maximizing Investigator’s Research Award (R35), American Association for Cancer Research (AACR) Tumor Microenvironment (TME) Junior Investigator, Researcher of the Year 2024 Award in the Department of Mechanical & Aerospace Engineering, NIH/NCI-designated UF Health Cancer Center Rising Star of the 2024 Year Award, and Faculty Advisor/Mentor of the Year 2025 Award in the Herbert Wertheim College of Engineering.
Education
Postdoc, 2017, Harvard University
Ph.D., 2013, University of Illinois at Urbana-Champaign
Teaching Interests
Active Soft Matter Biophysics; Biomechanics at Molecular, Cellular and Tissue Scales; Quantitative Optical Bio-imaging; Continuum Mechanics; and Finite-element Analysis
Research Interests
Biomechanics, Mechanobiology and Soft Matter: Cell and molecular mechanics in cancer development and metastasis, cardiovascular system, and neurons; unconventional mechano-electrophysiology; quantitative in vivo/vitro functional bio-imaging; bio-nanotechnology; and development of new biophysical tools to probe biological function/structure.
Recent Publications
Yin Xin, Keming Li , Miao Huang, Chenyu Liang, Dietmar Siemann, Lizi Wu, Youhua Tan, and Xin Tang, Biophysics in tumor growth and progression: from single mechano-sensitive molecules to mechanomedicine. 2023, Oncogene (Nature), https://www.nature.com/articles/s41388-023-02844-x.pdf.
Note: This article is selected as “The best of Oncogene 2023″.
Chenyu Liang, Qian Zhang, Xin Chen, Jiawei Liu, Mai Tanaka, Shu Wang, Sharon E. Lepler, Zeyuan Jin, Dietmar W. Siemann, Bo Zeng, and Xin Tang, Human cancer cells generate spontaneous calcium transients and intercellular waves that modulate tumor growth, Biomaterials (Impact Factor: 15.3), 2022, 290, 121823, https://www.sciencedirect.com/science/article/pii/S014296122200463X.
Chenyu Liang, Miao Huang, Tianqi Li, Lu Li, Hayley Sussman, Yao Dai, Dietmar W. Siemann, Mingyi Xie, and Xin Tang, Towards an integrative understanding of cancer mechanobiology: calcium, YAP, and microRNA under biophysical forces, Soft Matter (Impact Factor: 4.1), 2022,18, 1112-1148, https://pubs.rsc.org/en/content/articlelanding/2022/sm/d1sm01618k